Background: Standard medical treatments for patent ductus arteriosus (PDA) closure are, including indomethacin/ibuprofen and surgical ligation.Nowadays, a new strategy to close PDA is the use of paracetamol.The present study aimed to describe the use of intravenous (IV) paracetamol for PDA closure in neonates who present a contraindication to ibupr
Computer-aided prognosis of tuberculous meningitis combining imaging and non-imaging data
Abstract Tuberculous meningitis Egg Poachers (TBM) is the most lethal form of tuberculosis.Clinical features, such as coma, can predict death, but they are insufficient for the accurate prognosis of other outcomes, especially when impacted by co-morbidities such as HIV infection.Brain magnetic resonance imaging (MRI) characterises the extent and se
Review on preparation techniques of particle reinforced metal matrix composites
This paper reviews the investigation Sectional status of the techniques for preparation of metal matrix composites and the research outcomes achieved recently.The mechanisms, characteristics, application ranges and levels of development of these preparation techniques are analyzed.The advantages and the disadvantages of each technique are synthetic
Mito-LND and (E)-Akt inhibitor-IV: novel compounds inducing endoplasmic reticulum stress and ROS accumulation against hepatocellular carcinoma
Abstract Background Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality.Although multi-kinase inhibitors can prolong the overall survival of late-stage HCC patients, the emergence of drug resistance diminishes these benefits, ultimately resulting in treatment failure.Therefore, there is an urgent need for novel a